Three years after opening its first New York gallery, in an Upper East Side townhouse that previously housed the firm's private American office, Hauser & Wirth is extending its domain southward. Scheduled to open this fall, their massive new Chelsea space, on 18th Street near the West Side Highway, will be the gallery's seventh venue (joining three in London, two in Zurich--where it opened in 1992 in a former brewery--and the townhouse uptown).

The gallery represents an international roster of artists—including Louise Bourgeois, Paul McCarthy and Subodh Gupta—and lately has begun to work with younger artists. The current show is the first New York solo by 33-year-old Rashid Johnson.

Hauser & Wirth Chelsea will set up shop in a 1930s structure initially used as a stable and garage. The building's most famous tenant was the Roxy, in its heyday a hugely popular roller disco and nightclub. The 23,000-square-foot masonry building abuts the southern terminus of the High Line, near where the Whitney will open its new building in 2015.

The new space features a 20-foot-wide interior ramp, soaring ceilings and numerous skylights.

Gallery co-founder Iwan Wirth, who has long been on the lookout for a second New York location, said in 2009 that he had been visiting potential spaces for two years and "could absolutely imagine having a Hauser & Wirth space in Chelsea in the future."

Looks like that time has come.